AmeriQual Foods is headquartered in Evansville Indiana with the distinction of being the largest provider of Meals, Ready-to-eat (MREs) to the U.S. Military. Some of the reasons AmeriQual and numerous other companies have found success in Southwest Indiana include access to Ohio River Port Facilities, easy access to Evansville Regional Airport, multiple rail line accessibility and interstate motor carriers. Coupling these assets with a readily available workforce and access to a strong agricultural base, AmeriQual Foods and other companies such as Azteca Milling, Kerry Ingredients and Lewis Bakeries have found a good home in Southwest Indiana.

The Economic Development Coalition of Southwest Indiana acts as the umbrella organization for Gibson, Posey, Vanderburgh and Warrick Counties in Southwest Indiana. The Coalition facilitates and coordinates business retention, expansion and attraction activities; and, supports efforts to enhance the business climate through regional capacity building.